Cytokine Release Syndrome Is an Independent Risk Factor Associated With Platelet Transfusion Refractoriness After CAR-T Therapy for Relapsed/Refractory Acute Lymphoblastic Leukemia

• Main Authors: Yadan Liu (Author), Bin Liang (Author), Yan Liu (Author), Guoqing Wei (Author), Wenjun Wu (Author), Luxin Yang (Author), Li Yang (Author), He Huang (Author), Jue Xie (Author), Yongxian Hu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Chimeric antigen receptor T cell (CAR-T) therapy is successful in improving treatment outcomes for relapsed/refractory acute lymphoblastic leukemia (R/R ALL). However, toxicities associated with CAR-T therapy are being increasingly identified. Pancytopenia is one of the most common compl...