Functional impairment of human myeloid dendritic cells during Schistosoma haematobium infection.

• Main Authors: Bart Everts (Author), Ayola A Adegnika (Author), Yvonne C M Kruize (Author), Hermelijn H Smits (Author), Peter G Kremsner (Author), Maria Yazdanbakhsh (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic Schistosoma infection is often characterized by a state of T cell hyporesponsiveness of the host. Suppression of dendritic cell (DC) function could be one of the mechanisms underlying this phenomenon, since Schistosoma antigens are potent modulators of dendritic cell function in vitro. Yet,...