Improved Antitumor Effect of NK Cells Activated by Neutrophils in a Bone Marrow Transplant Model

• Main Authors: Daisuke Nakato (Author), Shotaro Iwamoto (Author), Keishiro Amano (Author), Takahiro Ito (Author), Hidemi Toyoda (Author), Ryo Hanaki (Author), Mari Morimoto (Author), Kaori Niwa (Author), Isao Tawara (Author), Kyoko Imanaka-Yoshida (Author), Masahiro Ogawa (Author), Masahiro Hirayama (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The licensing process mediated by inhibitory receptors of the Ly49 C-type lectin superfamily that recognizes self-major histocompatibility complex (MHC) class I in mice is essential for the proper antitumor function of natural killer (NK) cells. Several models for NK cell licensing can be exploited...