Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions.

• Main Authors: Alaullah Sheikh (Author), Rasheduzzaman Rashu (Author), Yasmin Ara Begum (Author), F Matthew Kuhlman (Author), Matthew A Ciorba (Author), Scott J Hultgren (Author), Firdausi Qadri (Author), James M Fleckenstein (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Enterotoxigenic Escherichia coli (ETEC), defined by their elaboration of heat-labile (LT) and/or heat-stable (ST) enterotoxins, are a common cause of diarrheal illness in developing countries. Efficient delivery of these toxins requires ETEC to engage target host enterocytes. This engagement is acco...