Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation

Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation

Abstract Background Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, a case was encountered in which the blood concentration of tacrolimus (TCR) at steady state increased after intravenous MTX adm...

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Main Authors: Chiaki Inoue (Author), Takehito Yamamoto (Author), Hiroshi Miyata (Author), Hiroshi Suzuki (Author), Tappei Takada (Author)
Format: Book
Published: BMC, 2023-12-01T00:00:00Z.
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