<i>Caesalpinia mimosoides</i> Leaf Extract Promotes Neurite Outgrowth and Inhibits BACE1 Activity in Mutant APP-Overexpressing Neuronal Neuro2a Cells

• Main Authors: Panthakarn Rangsinth (Author), Chatrawee Duangjan (Author), Chanin Sillapachaiyaporn (Author), Ciro Isidoro (Author), Anchalee Prasansuklab (Author), Tewin Tencomnao (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is implicated in the imbalance of several proteins, including Amyloid-β (Aβ), amyloid precursor protein (APP), and BACE1. APP overexpression interferes with neurite outgrowth, while BACE1 plays a role in Aβ generation. Medicinal herbs with effects on neurite outgrowth s...