Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis

• Main Authors: Wenchang Yang (Author), Yaxin Wang (Author), Peng Zhang (Author), Tao Wang (Author), Chengguo Li (Author), Xin Tong (Author), Xiangyu Zeng (Author), Yuping Yin (Author), Kaixiong Tao (Author), Ruidong Li (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

4-Octyl itaconate (OI) is a novel anti-inflammatory metabolite that exerts protective effects in many various disease models. However, its function in autoimmune hepatitis- (AIH-) associated hepatic injury has not been investigated. In this study, we successfully used concanavalin A (Con A) to estab...