Scoparone attenuates cholestatic liver injury through regulating hepatic bile acid metabolism, ameliorating periductal fibrosis and inhibiting inflammatory response

• Main Authors: Juan Hao (Author), Xiaoyu Shen (Author), Kan Lu (Author), Yi Xu (Author), Yiyue Chen (Author), Jibo Liu (Author), Xiaohong Shao (Author), Chunling Zhu (Author), Yaqin Ding (Author), Xin Xie (Author), Jian Wu (Author), Quanjun Yang (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Cholestatic liver disease (CLD) encompasses a broad spectrum of etiologically heterogeneous hepatobiliary disorders with common features, including ductal reaction, periductal fibrosis, and inflammatory response. Scoparone (SCO) is a bioactive component of the herbal medicine Artemisia c...