IL-2 Signaling Axis Defects: How Many Faces?

CD25, Signal transducer and activator of transcription 5B (STAT5B) and Forkhead box P3 (FOXP3) are critical mediators of Interleukin-2 (IL-2) signaling pathway in regulatory T cells (Tregs). CD25 (i.e., IL-2 Receptor α) binds with high affinity to IL-2, activating STAT5B-mediated signaling that even...

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Bibliographic Details
Main Authors: Filippo Consonni (Author), Claudio Favre (Author), Eleonora Gambineri (Author)
Format: Book
Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available