5α-Hydroxycostic acid inhibits choroidal neovascularization in rats through a dual signalling pathway mediated by VEGF and angiopoietin 2

• Κύριοι συγγραφείς: Wulong Lei (Συγγραφέας), Huan Xu (Συγγραφέας), Hao Yao (Συγγραφέας), Lanjiao Li (Συγγραφέας), Menglei Wang (Συγγραφέας), Xiyuan Zhou (Συγγραφέας), Xueqin Liu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2023-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background 5α-Hydroxycostic acid is a eudemane sesquiterpene that is isolated from the natural plant, Laggera alata. It exerts anti-inflammatory and anti-angiogenic effects on human breast cancer cells, but its role and underlying mechanism in choroidal neovascularization (CNV) are still un...