MicroRNA-135a-5p Promotes the Functional Recovery of Spinal Cord Injury by Targeting SP1 and ROCK

• Main Authors: Nanxiang Wang (Author), Yang Yang (Author), Mao Pang (Author), Cong Du (Author), Yuyong Chen (Author), Simin Li (Author), Zhenming Tian (Author), Feng Feng (Author), Yang Wang (Author), Zhenxiang Chen (Author), Bin Liu (Author), Limin Rong (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Emerging evidence indicates that microRNAs play a pivotal role in neural remodeling after spinal cord injury (SCI). This study aimed to investigate the mechanisms of miR-135a-5p in regulating the functional recovery of SCI by impacting its target genes and downstream signaling. The gene transfection...