The Sulfilimine Analogue of Allicin, <i>S</i>-Allyl-<i>S</i>-(<i>S</i>-allyl)-<i>N</i>-Cyanosulfilimine, Is Antimicrobial and Reacts with Glutathione

• Päätekijät: Tobias Horn (Tekijä), Wolfgang Bettray (Tekijä), Ulrike Noll (Tekijä), Felix Krauskopf (Tekijä), Meng-Ruo Huang (Tekijä), Carsten Bolm (Tekijä), Alan J. Slusarenko (Tekijä), Martin C. H. Gruhlke (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2020-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

When cells of garlic (<i>Allium sativum</i>) are disrupted by wounding, they produce the defense substance allicin (diallylthiosulfinate). Allicin is an efficient thiol trap and readily passes through cell membranes into the cytosol, where it behaves as a redox toxin by oxidizing the cel...