The Sulfilimine Analogue of Allicin, <i>S</i>-Allyl-<i>S</i>-(<i>S</i>-allyl)-<i>N</i>-Cyanosulfilimine, Is Antimicrobial and Reacts with Glutathione

The Sulfilimine Analogue of Allicin, <i>S</i>-Allyl-<i>S</i>-(<i>S</i>-allyl)-<i>N</i>-Cyanosulfilimine, Is Antimicrobial and Reacts with Glutathione

When cells of garlic (<i>Allium sativum</i>) are disrupted by wounding, they produce the defense substance allicin (diallylthiosulfinate). Allicin is an efficient thiol trap and readily passes through cell membranes into the cytosol, where it behaves as a redox toxin by oxidizing the cel...

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Main Authors: Tobias Horn (Author), Wolfgang Bettray (Author), Ulrike Noll (Author), Felix Krauskopf (Author), Meng-Ruo Huang (Author), Carsten Bolm (Author), Alan J. Slusarenko (Author), Martin C. H. Gruhlke (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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3rd Floor Main Library

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