The Sulfilimine Analogue of Allicin, <i>S</i>-Allyl-<i>S</i>-(<i>S</i>-allyl)-<i>N</i>-Cyanosulfilimine, Is Antimicrobial and Reacts with Glutathione

• Główni autorzy: Tobias Horn (Autor), Wolfgang Bettray (Autor), Ulrike Noll (Autor), Felix Krauskopf (Autor), Meng-Ruo Huang (Autor), Carsten Bolm (Autor), Alan J. Slusarenko (Autor), Martin C. H. Gruhlke (Autor)
• Format: Książka
• Wydane: MDPI AG, 2020-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

When cells of garlic (<i>Allium sativum</i>) are disrupted by wounding, they produce the defense substance allicin (diallylthiosulfinate). Allicin is an efficient thiol trap and readily passes through cell membranes into the cytosol, where it behaves as a redox toxin by oxidizing the cel...