Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis

• Main Authors: Madhusudan Grover (Author), Simon J. Gibbons (Author), Asha A. Nair (Author), Cheryl E. Bernard (Author), Adeel S. Zubair (Author), Seth T. Eisenman (Author), Laura A. Wilson (Author), Laura Miriel (Author), Pankaj J. Pasricha (Author), Henry P. Parkman (Author), Irene Sarosiek (Author), Richard W. McCallum (Author), Kenneth L. Koch (Author), Thomas L. Abell (Author), William J. Snape (Author), Braden Kuo (Author), Robert J. Shulman (Author), Travis J. McKenzie (Author), Todd A. Kellogg (Author), Michael L. Kendrick (Author), James Tonascia (Author), Frank A. Hamilton (Author), Gianrico Farrugia (Author), the NIDDK Gastroparesis Clinical Research Consortium (GpCRC) (Author)
• Format: Book
• Published: BMC, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cellular changes described in human gastroparesis have revealed a role for immune dysregulation, however, a mechanistic understanding of human gastroparesis and the signaling pathways involved are still unclear. Methods Diabetic gastroparetics, diabetic non-gastroparetic controls...