"Small is beautiful" - Examining reliable determination of low-abundant therapeutic antibody glycovariants

• 主要な著者: Katharina Böttinger (著者), Christof Regl (著者), Veronika Schäpertöns (著者), Erdmann Rapp (著者), Therese Wohlschlager (著者), Christian G. Huber (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2024-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Glycans associated with biopharmaceutical drugs play crucial roles in drug safety and efficacy, and therefore, their reliable detection and quantification is essential. Our study introduces a multi-level quantification approach for glycosylation analysis in monoclonal antibodies (mAbs), focusing on...