Antiproliferative and antimigratory effects of 3-(4-substituted benzyl)-5- isopropyl-5-phenylhydantoin derivatives in human breast cancer cells

• Main Authors: Ana Obradović (Author), Miloš Matić (Author), Branka Ognjanović (Author), Predrag Đurđević (Author), Emilija Marinković (Author), Gordana Ušćumlić (Author), Bojan Božić (Author), Biljana Božić Nedeljković (Author)
• Format: Book
• Published: Elsevier, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, a series of synthesized 3-(4-substituted benzyl)-5-isopropyl-5-phenylhydantoin derivatives as a potential antiproliferative and antimigratory agents were investigated. The possible antitumor mechanisms of investigated hydantoin derivatives were examined on human breast cancer cell lin...