Novel Small-Molecule Inhibitors of the SARS-CoV-2 Spike Protein Binding to Neuropilin 1

Furin cleavage of the SARS-CoV-2 spike protein results in a polybasic terminal sequence termed the C-end rule (CendR), which is responsible for the binding to neuropilin 1 (NRP1), enhancing viral infectivity and entry into the cell. Here we report the identification of 20 small-molecule inhibitors t...

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Main Authors: Anja Kolarič (Author), Marko Jukič (Author), Urban Bren (Author)
Format: Book
Published: MDPI AG, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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