Reversal of spatial memory impairment by phosphodiesterase 3 inhibitor cilostazol is associated with reduced neuroinflammation and increased cerebral glucose uptake in aged male mice

The nucleotide second messenger 3', 5'-cyclic adenosine monophosphate (cAMP) and 3', 5'-cyclic guanosine monophosphate (cGMP) mediate fundamental functions of the brain, including learning and memory. Phosphodiesterase 3 (PDE3) can hydrolyze both cAMP and cGMP and appears to be i...

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Main Authors: Shuichi Yanai (Author), Tetsuro Tago (Author), Jun Toyohara (Author), Tomoko Arasaki (Author), Shogo Endo (Author)
Format: Book
Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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