Optimizing the dosing schedule of l-asparaginase improves its anti-tumor activity in breast tumor-bearing mice
Proliferation of acute lymphoblastic leukemic cells is nutritionally dependent on the external supply of asparagine. l-asparaginase, an enzyme hydrolyzing l-asparagine in blood, is used for treatment of acute lymphoblastic leukemic and other related blood cancers. Although previous studies demonstra...
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| Egile Nagusiak: | , , , , |
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| Formatua: | Liburua |
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Elsevier,
2018-04-01T00:00:00Z.
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Internet
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A1234.567 |
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