NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.

• Main Authors: T Eoin West (Author), Nicolle D Myers (Author), Narisara Chantratita (Author), Wirongrong Chierakul (Author), Direk Limmathurotsakul (Author), Vanaporn Wuthiekanun (Author), Edward A Miao (Author), Adeline M Hajjar (Author), Sharon J Peacock (Author), H Denny Liggitt (Author), Shawn J Skerrett (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Burkholderia pseudomallei causes the tropical infection melioidosis. Pneumonia is a common manifestation of melioidosis and is associated with high mortality. Understanding the key elements of host defense is essential to developing new therapeutics for melioidosis. As a flagellated bacterium encodi...