GRKs and β-Arrestins: "Gatekeepers" of Mitochondrial Function in the Failing Heart

• Main Authors: Daniela Sorriento (Author), Jessica Gambardella (Author), Antonella Fiordelisi (Author), Guido Iaccarino (Author), Maddalena Illario (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondrial regulation of energy production, calcium homeostasis, and cell death are critical for cardiac function. Accordingly, the structural and functional abnormalities of these organelles (mitochondrial dysfunction) contribute to developing cardiovascular diseases and heart failure. Therefore...