Case Report: Post-Partum Complications of NFκB1 Deficiency Underscore a Need to Better Understand Primary Immunodeficiency Management During Pregnancy

• Main Authors: Diem-Tran I. Nguyen (Author), Amanda Grimes (Author), Donald Mahoney (Author), Sebastian Faro (Author), William T. Shearer (Author), Aaron L. Miller (Author), Nicholas L. Rider (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nuclear factor κappa-B (NFκB) is a family of transcription factors involved in regulating inflammation and immunity. Mutations in the NFκB1 pathway are associated with primary immune defects and underlie the most common monogenic etiology of common variable immunodeficiency (CVID). However, little i...