Interaction of Potent Mitochondrial Uncouplers with Thiol-Containing Antioxidants

• Ngā kaituhi matua: Ljudmila S. Khailova (Author), Alexander M. Firsov (Author), Elena A. Kotova (Author), Yuri N. Antonenko (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2019-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

It is generally considered that reactive oxygen species (ROS) are involved in the development of numerous pathologies. The level of ROS can be altered via the uncoupling of oxidative phosphorylation by using protonophores causing mitochondrial membrane depolarization. Here, we report that the uncoup...