Inhibition of Matrix Metalloproteinases and Cancer Cell Detachment by Ru(II) Polypyridyl Complexes Containing 4,7-Diphenyl-1,10-phenanthroline Ligands-New Candidates for Antimetastatic Agents

Inhibition of Matrix Metalloproteinases and Cancer Cell Detachment by Ru(II) Polypyridyl Complexes Containing 4,7-Diphenyl-1,10-phenanthroline Ligands-New Candidates for Antimetastatic Agents

Primary tumor targeting is the dominant approach in drug development, while metastasis is the leading cause of cancer death. Therefore, in addition to the cytotoxic activity of a series of Ru(II) polypyridyl complexes of the type [Ru(dip)<sub>2</sub>L]<sup>2+</sup> (dip: 4,7-...

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Main Authors: Przemysław Gajda-Morszewski (Author), Ilona Gurgul (Author), Ewelina Janczy-Cempa (Author), Olga Mazuryk (Author), Michał Łomzik (Author), Małgorzata Brindell (Author)
Format: Book
Published: MDPI AG, 2021-10-01T00:00:00Z.
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3rd Floor Main Library

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