Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians

• Main Authors: Qian Zeng (Author), Xiaoping Chen (Author), Chaoxue Ning (Author), Qiao Zhu (Author), Yao Yao (Author), Yali Zhao (Author), Fuxin Luan (Author)
• Format: Bog
• Udgivet: BMC, 2018-02-01T00:00:00Z.
• Fag: article
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Abstract Background Human aging is a hot topic in biology, and it has been associated with DNA methylation changes at specific genomic sites. We aimed to study the changes of DNA methylation at a single-CpG-site resolution using peripheral blood samples from centenarians. Methods Using Illumina 450 ...