Higher expression of CCL2, CCL4, CCL5, CCL21, and CXCL8 chemokines in the skin associated with parasite density in canine visceral leishmaniasis.

• Main Authors: Daniel Menezes-Souza (Author), Renata Guerra-Sá (Author), Cláudia Martins Carneiro (Author), Juliana Vitoriano-Souza (Author), Rodolfo Cordeiro Giunchetti (Author), Andréa Teixeira-Carvalho (Author), Denise Silveira-Lemos (Author), Guilherme Corrêa Oliveira (Author), Rodrigo Corrêa-Oliveira (Author), Alexandre Barbosa Reis (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: The immune response in the skin of dogs infected with Leishmania infantum is poorly understood, and limited studies have described the immunopathological profile with regard to distinct levels of tissue parasitism and the clinical progression of canine visceral leishmaniasis (CVL). METHO...