Regional Absorption of Fimasartan in the Gastrointestinal Tract by an Improved In Situ Absorption Method in Rats

• Main Authors: Tae Hwan Kim (Author), Soo Heui Paik (Author), Yong Ha Chi (Author), Jürgen B. Bulitta (Author), Da Young Lee (Author), Jun Young Lim (Author), Seung Eun Chung (Author), Chang Ho Song (Author), Hyeon Myeong Jeong (Author), Soyoung Shin (Author), Beom Soo Shin (Author)
• Format: Book
• Published: MDPI AG, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present study was to assess the regional absorption of fimasartan by an improved in situ absorption method in comparison with the conventional in situ single-pass perfusion method in rats. After each gastrointestinal segment of interest was identified, fimasartan was injected into the...