Observed reductions in Schistosoma mansoni transmission from large-scale administration of praziquantel in Uganda: a mathematical modelling study.

• Main Authors: Michael D French (Author), Thomas S Churcher (Author), Manoj Gambhir (Author), Alan Fenwick (Author), Joanne P Webster (Author), Narcis B Kabatereine (Author), Maria-Gloria Basáñez (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:To date schistosomiasis control programmes based on chemotherapy have largely aimed at controlling morbidity in treated individuals rather than at suppressing transmission. In this study, a mathematical modelling approach was used to estimate reductions in the rate of Schistosoma mansoni...