Do Increased Doses to Stem-Cell Niches during Radiation Therapy Improve Glioblastoma Survival?

• Main Authors: Sebastian Adeberg (Author), Semi Ben Harrabi (Author), Nina Bougatf (Author), Denise Bernhardt (Author), Angela Mohr (Author), Juliane Rieber (Author), Christian Koelsche (Author), Stefan Rieken (Author), Juergen Debus (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Purpose. The reasons for the inevitable glioblastoma recurrence are yet understood. However, recent data suggest that tumor cancer stem cells (CSCs) in the stem-cell niches, with self-renewing capacities, might be responsible for tumor initiation, propagation, and recurrence. We aimed...