Plasma Fibrinogen Is a Natural Deterrent to Amyloid β-Induced Platelet Activation and Neuronal Toxicity

• Main Authors: Vijay K Sonkar (Author), Paresh P Kulkarni (Author), Susheel N Chaurasia (Author), Ayusman Dash (Author), Abhishek Jauhari (Author), Devendra Parmar (Author), Sanjay Yadav (Author), Debabrata Dash (Author)
• Format: Book
• Published: BMC, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Alzheimer's disease (AD) is a devastating neurodegenerative disorder, characterized by extensive loss of neurons and deposition of amyloid β (Aβ) in the form of extracellular plaques. Aβ is considered to have a critical role in synaptic loss and neuronal death underlying cognitive decl...