Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers

• Main Authors: Khalid K. Alam (Author), Jonathan L. Chang (Author), Margaret J. Lange (Author), Phuong D.M. Nguyen (Author), Andrew W. Sawyer (Author), Donald H. Burke (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aptamer selections often yield distinct subpopulations, each with unique phenotypes that can be leveraged for specialized applications. Although most selections aim to attain ever higher specificity, we sought to identify aptamers that recognize increasingly divergent primate lentiviral reverse tran...