Metformin: A Potential Therapeutic Tool for Rheumatologists

• Main Authors: Teresa Salvatore (Author), Pia Clara Pafundi (Author), Raffaele Galiero (Author), Klodian Gjeloshi (Author), Francesco Masini (Author), Carlo Acierno (Author), Anna Di Martino (Author), Gaetana Albanese (Author), Maria Alfano (Author), Luca Rinaldi (Author), Ferdinando Carlo Sasso (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metformin is an oral antihyperglycemic drug widely used to treat type 2 diabetes, acting via indirect activation of 5' Adenosine Monophosphate-activated Protein Kinase (AMPK). Actually, evidence has accumulated of an intriguing anti-inflammatory activity, mainly mediated by AMPK through a varie...