Association between promoter -1607 polymorphism of <it>MMP1 </it>and Lumbar Disc Disease in Southern Chinese

• Main Authors: Leong John CY (Author), Yip Shea-Ping (Author), Luk Keith DK (Author), Fan Bao-Jian (Author), Kao Patrick YP (Author), Karppinen Jaro (Author), Ho Daniel WH (Author), Song You-Qiang (Author), Cheah Kathryn SE (Author), Sham Pak (Author), Chan Danny (Author), Cheung Kenneth MC (Author)
• Format: Book
• Published: BMC, 2008-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix of the intervertebral disc. A SNP for guanine insertion/deletion (G/D), the -1607 promoter polymorphism, of the <it>MMP1 </it>ge...