Experimental in vivo models for understanding inter-molecular interactions and preventing multifactor disease development

• Main Authors: Iskra Sainova (Author), Vera Kolyovska (Author), Veselin Nanev (Author), Desislava Drenska (Author), Dimitar Maslarov (Author), Dimitrina Dimitrova-Dikanarova (Author), Tzvetanka Markova (Author)
• Format: Book
• Published: Pensoft Publishers, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The increased spontaneous fragility in the centromere regions of the chromosomes predisposes to abnormal cellular division due to abnormal interaction with the mitotic spindle, which leads to number chromosomal aberrations. The abnormal structure of the microtubule-associated proteins (MAPs) could a...