Comparative Assessment and High-Throughput Drug-Combination Profiling of TEAD-Palmitoylation Inhibitors in Hippo Pathway Deficient Mesothelioma

The hippo signaling pathway is a central tumor suppressor cascade frequently inactivated in selected human cancers, leading to the aberrant activation of TEAD transcription factors. Whereas several TEAD auto-palmitoylation inhibitors are currently in development, a comprehensive assessment of this n...

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Main Authors: Lale Evsen (Author), Patrick J. Morris (Author), Craig J. Thomas (Author), Michele Ceribelli (Author)
Format: Book
Published: MDPI AG, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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