Tumor Necrosis Factor-α Mediates Lung Injury in the Early Phase of Endotoxemia

• Main Authors: Kung-Yen Chen (Author), Chao-Yuan Chang (Author), Hao-Jen Hsu (Author), Hung-Jen Shih (Author), I-Tao Huang (Author), Hemal H. Patel (Author), Chun-Jen Huang (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endotoxemia induces lung injury. We assessed the therapeutic efficacy between triple cytokine (tumor necrosis factor-α [TNF-α], interleukin-1β [IL-1β], and IL-6) inhibition (mediated by KCF18 peptide) and single cytokine (TNF-α) inhibition (mediated by SEM18 peptide) on alleviating lung injury in th...