Activation of Nrf2/HO-1 Antioxidant Pathway by Heme Attenuates Calcification of Human Lens Epithelial Cells

• Main Authors: Arpan Chowdhury (Author), Enikő Balogh (Author), Haneen Ababneh (Author), Andrea Tóth (Author), Viktória Jeney (Author)
• Formato: Libro
• Publicado: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Cataract, an opacification in the crystalline lens, is a leading cause of blindness. Deposition of hydroxyapatite occurs in a cataractous lens that could be the consequence of osteogenic differentiation of lens epithelial cells (LECs). Nuclear factor erythroid 2-related factor 2 (Nrf2) controls the...