Case report: Multiple epstein-barr virus-associated smooth muscle tumours in a child with IL-2-inducible T-cell kinase mutation of undetermined clinical significance

• Main Authors: Qiongli Wen (Author), Jing Ning (Author), Zhiqun Mao (Author), Xiangdang Long (Author), Xiangling He (Author), Zhihong Chen (Author), Qiuyi Di (Author), Qiaorong Li (Author), Yu Zhuo (Author), Gang Zhong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundEBV-associated smooth muscle tumours (EBV-SMTs) are uncommon neoplasms associated with immunodeficiency. The pathogenesis of EBV-SMTs is poorly understood. IL-2-inducible T-cell kinase (ITK), a member of the Tec family of tyrosine kinases, is the predominant Tec kinase in T cells. Research...