Inhibition of post-trabeculectomy fibrosis via topically instilled antisense oligonucleotide complexes co-loaded with fluorouracil

• المؤلفون الرئيسيون: Kuan Jiang (مؤلف), Junyi Chen (مؤلف), Lingyu Tai (مؤلف), Chang Liu (مؤلف), Xishan Chen (مؤلف), Gang Wei (مؤلف), Weiyue Lu (مؤلف), Weisan Pan (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2020-09-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Trabeculectomy is the mainstay of surgical glaucoma treatment, while the success rate was unsatisfying due to postoperative scarring of the filtering blebs. Clinical countermeasures for scar prevention are intraoperative intervention or repeated subconjunctival injections. Herein, we designed a co-d...