Intrathecal Pseudodelivery of Drugs in the Therapy of Neurodegenerative Diseases: Rationale, Basis and Potential Applications

• Main Authors: Menéndez-González Manuel (Author), Bogdan-Ionel Tamba (Author), Maxime Leclere (Author), Mostafa Mabrouk (Author), Thomas-Gabriel Schreiner (Author), Romeo Ciobanu (Author), Tomás-Zapico Cristina (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intrathecal pseudodelivery of drugs is a novel route to administer medications to treat neurodegenerative diseases based on the CSF-sink therapeutic strategy by means of implantable devices. While the development of this therapy is still in the preclinical stage, it offers promising advantages over...