Polymorphism of TPH2 gene rs120074175 is not associated with risk factors of schizophrenia

• Main Authors: James P Laksono (Author), Riyadi Sumirtanurdin (Author), Haafizah Dania (Author), Fitri N Ramadhani (Author), Dyah A Perwitasari (Author), Rizky Abdulah (Author), Melisa I Barliana (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context: Polymorphism on tryptophan hydroxylase 2 (TPH2) gene rs120074175 can cause the synthesis of neurotransmitter serotonin in the brain to reduce up to 80%. Reduced serotonin in the brain can cause dopamine release to occur continuously. Excess dopamine in the brain may cause positive symptom o...