Sequestration of Voriconazole and Vancomycin Into Contemporary Extracorporeal Membrane Oxygenation Circuits: An in vitro Study

• Main Authors: Genny Raffaeli (Author), Giacomo Cavallaro (Author), Karel Allegaert (Author), Birgit C. P. Koch (Author), Fabio Mosca (Author), Dick Tibboel (Author), Enno D. Wildschut (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Bacterial and fungal infections are common and often contribute to death in patients undergoing extracorporeal membrane oxygenation (ECMO). Drug disposition is altered during ECMO, and adsorption in the circuit is an established causative factor. Vancomycin and voriconazole are widely us...