The Effect of a Novel Serine Protease Inhibitor on Inflammation and Intestinal Permeability in a Murine Colitis Transfer Model

• Hlavní autoři: Hanne Van Spaendonk (Autor), Hannah Ceuleers (Autor), Annemieke Smet (Autor), Maya Berg (Autor), Jurgen Joossens (Autor), Pieter Van der Veken (Autor), Sven M. Francque (Autor), Anne-Marie Lambeir (Autor), Joris G. De Man (Autor), Ingrid De Meester (Autor), Koen Augustyns (Autor), Benedicte Y. De Winter (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Background: A protease/antiprotease disbalance is observed in inflammatory bowel diseases (IBD). We therefore studied the effect of the novel serine protease inhibitor UAMC-00050 on intestinal inflammation and permeability in a chronic colitis T cell transfer mouse model to get further insight into...