BK Channel in the Physiology and in the Cancer of Pancreatic Duct: Impact and Reliability of BK Openers

• Main Authors: Paolo Zuccolini (Author), Paola Gavazzo (Author), Michael Pusch (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

BK (KCa 1.1, Slo-1) is a K+ channel characterized by an allosteric regulation of the gating mechanism by Ca2+ binding and voltage, and a high unitary conductance. The channel is expressed in many different tissues, where it is involved in the regulation or the fine-tuning of many physiological proce...