Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB

• Main Authors: Solomon Leigh A (Author), Ali Shadan (Author), Banerjee Sanjeev (Author), Munkarah Adnan R (Author), Morris Robert T (Author), Sarkar Fazlul H (Author)
• Format: Book
• Published: BMC, 2008-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Platinum-resistance (PR) continues to be a major problem in the management of epithelial ovarian cancer (EOC). Response to various chemotherapeutic agents is poor in patients deemed PR. Genistein, a soy isoflavone has been shown to e...