Xanthine oxidase inhibition study of isolated secondary metabolites from Dolichandrone spathacea (Bignoniaceae): In vitro and in silico approach

• Main Authors: Dang-Khoa Nguyen (Author), Ta-Wei Liu (Author), Su-Jung Hsu (Author), Quoc-Dung Tran Huynh (Author), Truc-Ly Thi Duong (Author), Man-Hsiu Chu (Author), Yun-Han Wang (Author), Thanh-Hoa Vo (Author), Ching-Kuo Lee (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Xanthine oxidase (XO) has been widely recognized as a pivotal enzyme in developing hyperuricemia, primarily contributing to the excessive production of uric acid during purine metabolism in the liver. One of the standard treatment approaches involves reducing uric acid levels by inhibiting XO activi...