Differential effects of SARM1 inhibition in traumatic glaucoma and EAE optic neuropathies

• Main Authors: Pingting Liu (Author), Wei Chen (Author), Haowen Jiang (Author), Haoliang Huang (Author), Liping Liu (Author), Fang Fang (Author), Liang Li (Author), Xue Feng (Author), Dong Liu (Author), Roopa Dalal (Author), Yang Sun (Author), Paymaan Jafar-Nejad (Author), Karen Ling (Author), Frank Rigo (Author), Jiangbin Ye (Author), Yang Hu (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Optic neuropathy is a group of optic nerve (ON) diseases with progressive degeneration of ON and retinal ganglion cells (RGCs). The lack of neuroprotective treatments is a central challenge for this leading cause of irreversible blindness. SARM1 (sterile α and TIR motif-containing protein 1) has int...