Guanine inhibits the growth of human glioma and melanoma cell lines by interacting with GPR23

• Main Authors: Roberta Garozzo (Author), Mariachiara Zuccarini (Author), Patricia Giuliani (Author), Valentina Di Liberto (Author), Giuseppa Mudò (Author), Francesco Caciagli (Author), Renata Ciccarelli (Author), Francisco Ciruela (Author), Patrizia Di Iorio (Author), Daniele F. Condorelli (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Guanine-based purines (GBPs) exert numerous biological effects at the central nervous system through putative membrane receptors, the existence of which is still elusive. To shed light on this question, we screened orphan and poorly characterized G protein-coupled receptors (GPRs), selecting those t...