Structure-based design of oligomeric receptor-binding domain (RBD) recombinant proteins as potent vaccine candidates against SARS-CoV-2

The receptor-binding domain (RBD) of SARS-CoV-2 S protein is proved to be the major target of neutralizing antibodies. However, on the S protein, only a portion of epitopes in RBD can be effectively displayed with dynamic changes in spatial conformations. Using RBD fragment as antigen can better exp...

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Main Authors: Ting Zhang (Author), Ningchen Zheng (Author), Zhirong Wang (Author), Xuemei Xu (Author)
Format: Book
Published: Taylor & Francis Group, 2023-01-01T00:00:00Z.
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