Repurposing Mitomycin C in Combination with Pentamidine or Gentamicin to Treat Infections with Multi-Drug-Resistant (MDR) <i>Pseudomonas aeruginosa</i>

• Main Authors: Elin Svedholm (Author), Benjamin Bruce (Author), Benjamin J. Parcell (Author), Peter J. Coote (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2024-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The aims of this study were (i) to determine if the combination of mitomycin C with pentamidine or existing antibiotics resulted in enhanced efficacy versus infections with MDR <i>P. aeruginosa</i> in vivo; and (ii) to determine if the doses of mitomycin C and pentamidine in combination...