Doxycycline and Benznidazole Reduce the Profile of Th1, Th2, and Th17 Chemokines and Chemokine Receptors in Cardiac Tissue from Chronic Trypanosoma cruzi-Infected Dogs

• Main Authors: Guilherme de Paula Costa (Author), Laís Roquete Lopes (Author), Maria Cláudia da Silva (Author), Aline Luciano Horta (Author), Washington Martins Pontes (Author), Cristiane M. Milanezi (Author), Paulo Marcos da Mata Guedes (Author), Wanderson Geraldo de Lima (Author), Richard Schulz (Author), João Santana da Silva (Author), Andre Talvani (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemokines (CKs) and chemokine receptors (CKR) promote leukocyte recruitment into cardiac tissue infected by the Trypanosoma cruzi. This study investigated the long-term treatment with subantimicrobial doses of doxycycline (Dox) in association, or not, with benznidazole (Bz) on the expression of CK...